2024 Bongkrekic acid-13c28

Bongkrekic acid-13c28

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WebBongkrekic acid is a mitochondrial ANT toxin and is reported primarily in outbreaks of food-borne poisoning involving coconut and corn. It should be considered in outbreaks of food … WebThe antibiotic bongkrekic acid is shown to inhibit the phosphorylation of added ADP coupled with either the reactions of the respiratory chain or the dismutation of α-ketoglutarate in mammalian mitochondria. It also prevents the utilization of ATP for energy-linked cation transport and in energy dissipation by uncoupling agents. However, …

Bongkrekic Acid - an overview ScienceDirect Topics

WebMay 20, 1991 · Here we demonstrate that bongkrekic acid, a potent inhibitor of the mitochondrial ATP/ADP translocase, inhibits glucose-induced electrical activity in the pancreatic β-cell through the simulation of ATP-sensitive potassium channel (K-ATP-channel) activity. WebBongkrekic acid is a mitochondrial toxin secreted by the bacteria Pseudomonas cocovenenans. Bongkrekic acid specific ligand for mitochondrial adenine nucleotide translocase (ANT) rather than the … code for tiny town tycoon

Bongkrek acid - Wikipedia

WebC 28 H 38 O 7. CAS number: 11076-19-0. EU number: Not assigned. Fermentek product code: BON. Source: Pseudomonas gladioli. WebFor example, bongkrekic acid, or exposure to uncouplers such as p -trifluoromethoxy carbonyl cyanide phenyl hydrazone (FCCP) to moderate Ca 2+ uptake during excitotoxicity, correspondingly moderate mitochondrial dysfunction and cell death in the short term. 105,106 However, by preventing mitochondrial adenylate exchange, and by uncoupling … WebOct 24, 2024 · Bongkrekic acid, produced by the bacterium, Burkholderia cocovenenans, is heat-stable and cannot be removed by washing. It has been implicated in outbreaks of foodborne illness involving... code for todd\u0027s room sally face

BONGKREKIC ACID 11076-19-0 - ChemicalBook

Bongkrekic Acid Poisoning From Fermented Food

WebAbstract An efficient total synthesis of (+)-bongkrekic acid, a potent apoptosis inhibitor, has been accomplished by employing a convergent strategy based on the Suzuki-Miyaura coupling of three fully functionalized segments. All Science Journal Classification (ASJC) codes Catalysis Organic Chemistry Fingerprint WebDec 14, 2024 · This genus of fungi produces lipophilic and highly toxic 3-nitropropionic acid (3-NPA), which causes severe encephalopathy (disease of the brain that alters brain function or structure). This explained the symptoms in AC which were like those caused by bongkrekic acid. code for tmnt legends packWebBongkrekic acid (BKA) is an inhibitor of adenine nucleotide translocase (ANT). Since inhibition of ANT is connected to the inhibition of cytochrome c release from mitochondria, which then results in the suppression of apoptosis, it has been used as a tool for the mechanistic investigation of apoptosis. calories in chicken roll lunch meat

"WebJan 1, 2024 · Consumption of sufficient quantities of bongkrekic acid initially results in hyperglycemia, followed quickly by hypoglycemia that depletes the glycogen reserves in various tissues, including the heart and liver [5].A variety of symptoms are observed 4–6 h after consumption before lapsing into a coma, with death occurring 1–20 h after symptom … " - Bongkrekic acid-13c28

Bongkrekic acid-13c28

Bongkrekic acid poisoning: Severe liver function damage …

WebSep 20, 2024 · Bongkrekic acid is produced by the bacterium, Burkholderia cocovenenans, which is ubiquitous in the soil and plants. It grows best at 37°C and can optimally produce bongkrekic acid at about 26°C. Bongkrekic acid is heat-stable and cannot be removed by washing. Patients suffering from bongkrekic acid poisoning may show symptoms … WebIso-bong: A versatile first synthesis of isobongkrekic acid (IBA) has been developed. Key steps include three different palladium cross-couplings and an asymmetric homopropargylation. In-depth synthetic studies reveal the challenges faced in generating the right geometry of each diene. Abstract

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Web米酵菌酸（Bongkrek acid、bongkrekic acid ）是發酵的椰子受唐菖蒲伯克氏菌污染，產生的呼吸毒素。米酵菌酸被認為可能是食用椰子製成的丹貝（於印度尼西亚禁止販售）之致 …

WebBongkrekic acid solution (Pseudomonas cocovenenans, >= 95% HPLC, ~ 1mg/mL); Bongkrekic acid solution has been used as an adenine nucleotide translocator (ANT) … WebPribolab®. - Model STD#1201U - U- [13C28]-Bongkrekic acid-5 µg/mL-Methanol. From Mycotoxins. Share. Mycotoxin 13C stable isotope labeled internal standards are stable, …

WebBongkrek acid (also known as bongkrekic acid) is a respiratory toxin produced in fermented coconut or corn contaminated by the bacterium Burkholderia gladioli pathovar … WebThe inhibitors atractyloside and bongkrekic acid trap the AACs in two different conformations known as the c- and m-state where the carrier is open to the cytoplasmic …

WebThe symptoms of 3-NPA toxicity in humans are similar to those for bongkrekic acid, as described regarding sugar cane poisoning in humans in China and Africa, including initial gastrointestinal symptoms with vomiting and diarrhea and progressing encephalopathy leading to coma and death (8,11,12).

WebNational Center for Biotechnology Information. 8600 Rockville Pike, Bethesda, MD, 20894 USA. Contact. Policies. FOIA. HHS Vulnerability Disclosure. National Library of Medicine. National Institutes of Health. Department of Health and Human Services. code for thigh high compression stockingsWebJul 9, 2015 · Bongkrekic Acid In humans though, toxicity manifests within a few hours of ingestion and presents with abdominal pain, general discomfort, sweating, fatigue, and eventual coma. Death can occur within 24 hours. calories in chicken stir fry with vegetablesWebDec 18, 2024 · Poisoning incidents caused by bongkrekic acid (BA), one of the metabolites of Burkholderia gladioli pathovar cocovenenans ( B. cocovenenans ), have been reported in Indonesia, Mozambique, and China. The reported case fatality rates averaged 60%, 32%, and 26.5%, respectively. calories in chicken tamale homemadeWebBongkrekic acid C28H38O7 - PubChem Apologies, we are having some trouble retrieving data from our servers... PUGVIEW FETCH ERROR: 403 Forbidden National Center for Biotechnology Information 8600 Rockville … calories in chicken satayWebBongkrekic acid affects the liver, brain and kidneys, causing symptoms including lack of energy, dizziness, drowsiness, abdominal pain, vomiting etc. In severe cases, consuming food contaminated with Bongkrekic acid can be life threatening. What is SFA doing to reduce food safety risks from Bongkrekic Acid? code for topological sortWebBongkrekic acid (BA) is a sort of fatty acid produced by the bacterium Burkholderia gladioli pv. Cocovenenans, which survives in corn flour and coconut products (Travis M Falconer et al., 2016). First documented food poisoning case due to BA happened in Indonesia in 1895. calories in chicken skinWebMolecular Weight: 486.61 (free acid) Molecular Formula: C 28 H 38 O 7 Solubility: Miscible with DMSO. Physical Properties: Solution at 1 mg/mL (2 mM) in 0.01M Tris buffer pH 7.5 (contains 1 mg net bongkrekic acid per mL) Purity: 97% by HPLC NMR (Conforms) Storage Temperature: -20° Stability: Stable for 1 year from date of purchase as supplied. calories in chicken tenders baked