WebHuman chromosome 7 open reading frame 24 (C7orf24)/γ-glutamyl cyclotransferase has been suggested to be a potential diagnostic marker for several cancers, including … WebFeb 1, 2007 · Proteome analysis of bladder cancer with narrow‐range pH 2‐DE has identified a novel protein on chromosome 7 encoded by ORF 24 (C7orf24) as one of the highly expressed proteins in cancer cells. C7orf24 is currently registered in the protein database as a hypothetical protein with unknown function. The homologs of C7orf24 in …
Gamma-Glutamylcyclotransferase: A Novel Target Molecule for
WebThe identification and structural characterization of C7orf24 as γ-glutamyl cyclotransferase. An essential enzyme in the γ-glutamyl cycle. VOLUME 283 (2008) PAGES 22031-22042. Previous Article Inhibition of Fatty-acid Synthase Induces Caspase-8-mediated Tumor Cell Apoptosis by Up-regulating DDIT4* WebJul 12, 2013 · C7orf24—named after a hypothetical gene product of human chromosome 7 open reading frame 24—was originally identified as a cytoplasmic protein specifically expressed in the urothelial carcinoma ( 1, 2 ). Aberrant expression of C7orf24 has also been reported in a range of cancers, including prostate and breast cancers ( 3–7 ). ccg deck box
Solution structure of At3g28950 from Arabidopsis thaliana - PMC
WebMay 1, 2008 · The next highest match is the human protein C7orf24, whose crystal structure was recently solved by the CESG 17. This protein of unknown function displays 23.2% sequence identify with At3g28950 and alignment over 99 C α 18. Several cancer cell lines also express C7orf24, and siRNA knock-down of protein levels produced an … WebProteome analysis of bladder cancer with narrow-range pH 2-DE has identified a novel protein on chromosome 7 encoded by ORF 24 (C7orf24) as one of the highly expressed proteins in cancer cells. C7orf24 is currently registered in the protein database as a hypothetical protein with unknown function. WebWe have identified C7orf24 as -glutamyl cyclotransferase (GGCT),2a poorly studied enzyme in the -glutamyl cycle. -glutamyl cycle involves the synthesis of glutathione and its utilization in the uptake of amino acids, particularly in the renal tubule and across the blood-brain barrier in the cho- roid plexus in the brain (4, 5) (Fig. 1). buster keaton best stunts youtube