Can phenytoin cause folate deficiency
WebCauses of this type of anemia include: Too little folic acid in your diet; Hemolytic anemia; Long-term alcoholism; Use of certain medicines (such as phenytoin [Dilantin], … WebMar 21, 2024 · A folate deficiency can be caused by a lack of folate in the diet, medical conditions, drinking too much alcohol, gene mutations, and side effects of medications. …
Can phenytoin cause folate deficiency
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WebMar 13, 2024 · Folate deficiency classically presents as megaloblastic anaemia, with absence of neurological signs. Common causes include malabsorption, drugs and toxins, states of increased demand, and dietary deficiency. Hereditary folate malabsorption and other inborn errors of folate metabolism are rare causes. In early disease, haemoglobin … WebOct 22, 2015 · Phenytoin does not seem to have any effect on the folate metabolism pathways, nor does it appear to affect the excretion of folate. 27 However, most antiseizure medications increase hepatic ...
WebFeb 23, 2024 · Therefore, the above analysis has witnessed that the long-term phenytoin treatment was the cause for the deficiency of Vitamin B12 or Folate concentration of … WebA case of a patient who developed symptomatic phenytoin-induced folic acid deficiency is reported. Folate supplementation of 5 mg/d was followed by a decrease of serum …
WebConclusions: Folic acid supplementation should be initiated each time phenytoin therapy commences because of the hypothesized cofactor mechanism, decreased adverse … WebFolic acid deficiency causes. Isolated folate deficiency is rare in the United States and folic acid deficiency can arise from multiple causes, including inadequate dietary intake. …
WebMar 9, 2011 · Commonly used antiepileptic drugs (AEDs) can cause vitamin B 12 or folate deficiency, which is, in turn, associated with hyperhomocysteinemia, new research …
WebFolate deficiency anemia can occur if you don’t get enough folate in your diet. Other causes include conditions that prevent your body from absorbing or using folate, such as: Alcohol use disorder. Dialysis treatment for kidney failure. Digestive diseases, including Crohn’s disease and celiac disease. rainey hanley wells fargoWebFolate deficiency is common. Because the body stores only a small amount of folate, a diet lacking in folate leads to a deficiency within a few months. Not eating enough raw leafy vegetables and citrus fruits can cause folate deficiency. Anemia can develop, causing fatigue, paleness, irritability, shortness of breath, and dizziness. rainey hartwell paWebAccording to the People's Pharmacy, phenytoin was first discovered in 1908, although it was not used to treat seizure disorders until 1938. The oldest anti-epilepsy drug on the market today, Dilantin carries with it many side effects, from folic acid deficiency to recurrent neuro-toxicity. rainey handbagsWebFolate deficiency means you have a lower-than-normal amount of folic acid, a type of vitamin B, in your blood. Causes Folic acid (vitamin B9) works with vitamin B12 and … rainey hamiltonWebFolate deficiency can cause severe birth defects called neural tube defects. Neural tube defects include spina bifida and anencephaly . Folate deficiency can also increase your … rainey glass morrilton arWebPhenytoin has been associated with drug-induced gingival enlargement (overgrowth of the gums), probably due to above-mentioned folate deficiency; indeed, evidence from a randomized controlled trial suggests that folic acid supplementation can prevent gingival enlargement in children who take phenytoin. [32] rainey hartwellWebAug 13, 2024 · Uses of Folate. Folate Deficiency. Side Effects. Dosage. Toxicity. Folate is the natural form of vitamin B9 that the body needs to maintain its genetic building blocks, DNA and RNA. 1 However, folate is water-soluble, meaning the body does not store it, and you need to replenish it regularly through your diet. rainey gutters rochester mn