WebMar 23, 2024 · Four proteins (LPL, ASPN, CPVL and VSIR) identified in primary LV and RV cardiomyocytes were not detected in early-stage (days 10–16) or middle-stage (days 20–31) hPSC-CMs but were present in late-stage (days 50–93) hPSC-CMs (Fig. 6d). Of these, lipoprotein lipase (LPL) is a drug target for cardiovascular disease 33. These … WebCPVL shares 43% sequence identity with the vitellogenic carboxypeptidase protein that is expressed in mosquito ovaries. RT-PCR revealed strong CPVL expression in monocytic …
CPVL - Wikipedia
WebImmune cell lineage distribution i The RNA data was used to cluster genes according to their expression across single cell types. Clusters contain genes that have similar expression patterns, and each cluster has been manually annotated to describe common features in terms of function and specificity. Probable serine carboxypeptidase CPVL is an enzyme that in humans is encoded by the CPVL gene. The "CPVL" gene is expressed mainly in monocytes and macrophages, and it is located in the endoplasmatic reticulum and in the endosomal/lysosomal compartment. The distribution of CPVL … See more Gene "CPVL" gene is located at chromosome 7p15.1, consisting of 14 exons. At least two alternatively spliced transcripts which encode the same protein have been observed. See more Although the primary sequence of CPVL bears every hallmarks of a serine carboxypeptidase, the enzymatic function of CPVL has not … See more • Human CPVL genome location and CPVL gene details page in the UCSC Genome Browser. See more The deletion of this gene has been reported associated with Wilms tumor. GWAS show that genetic variations of the CPVL gene are associated with susceptibility to diabetic nephropathy in European Americans, Japanese and Chinese. CPVL is … See more • Maruyama K, Sugano S (January 1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. See more blighton
CPVL protein expression summary - The Human Protein …
WebNov 16, 2024 · CPVL was significantly upregulated in glioma cells and tissues compared with normal cells and tissues, respectively. Moreover, high CPVL expression was correlated with advanced clinical grade and poor prognosis. Silencing of CPVL promoted glioma cell apoptosis, and it inhibited cell proliferation and tumorigenicity in vitro and in vivo. WebCpvl Mouse Gene Details carboxypeptidase, vitellogenic-like International Mouse Phenotyping Consortium Gene: Cpvl MGI:1918537 Gene Summary Name: carboxypeptidase, vitellogenic-like Synonyms: 4933436L16Rik Order Alleles IMPC Data Collections Body Weight Measurements No Embryo Imaging Data Viability Data IMPC … WebCell line expression cluster i The RNA data was used to cluster genes according to their expression across cell lines. Clusters contain genes that have similar expression patterns, and each cluster has been manually annotated to describe common features in terms of function and specificity. frederick mosch