Inter-alpha-trypsin inhibitor heavy chain
Nettet3. jun. 2014 · Inter-alpha-trypsin inhibitor heavy chain H4 (ITIH4) is a 120 kDa acute-phase glycoprotein produced primarily in the liver, secreted into the blood, and identified in serum. ITIH4 is involved in liver development and stabilization of the extracellular matrix (ECM), and its expression is altered in liver disease. Nettet26. sep. 2024 · Itih3 inter-alpha trypsin inhibitor, heavy chain 3 [ (house mouse)] Gene ID: 16426, updated on 26-Sep-2024 Summary This gene encodes one of the heavy …
Inter-alpha-trypsin inhibitor heavy chain
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Nettet28. jan. 2008 · The inter-alpha-trypsin inhibitors (ITI) are a family of plasma protease inhibitors, assembled from a light chain – bikunin, encoded by AMBP – and five homologous heavy chains (encoded by ITIH1, ITIH2, ITIH3, ITIH4, and ITIH5 ), contributing to extracellular matrix stability by covalent linkage to hyaluronan. Nettet23. feb. 2024 · Inter-alpha-trypsin inhibitor heavy chain H5 −4.4 RBP4 Retinol-binding protein 4 2.8 APOA1 Apolipoprotein A-I −3.8 COL1A2 Collagen alpha-2(I) chain 2.6 ADAMTS1 A disintegrin and metalloproteinase with thrombospondin motifs 1 −3.4 LTF Lactotransferrin 2.3 B4GALT1 Beta-1,4-galactosyltransferase 1 −3.3 APOC3
NettetThe inter-α-trypsin inhibitor (IαI)1 family, a typical and classical example for protein-glycosaminoglycan-protein (PGP) complexes, occurs constitutively in plasma at relatively high concentrations and is a result of alternate combinations of three kinds of heavy chains with a common light chain, the bikunin proteoglycan. The family is … NettetAbbreviations: APOF, apolipoprotein F; ITIH4, inter-alpha-trypsin inhibitor heavy chain 4; PM 10, particulate matter ≤10 μm; PRG4, proteoglycan 4. Figure 4 shows the ROC curve of the sensitivity and specificity obtained for the PRG4, ITIH4, and APOF levels when discriminating between the ≥50 μg/m 3 and <50 μg/m 3 average 3-year PM 10 …
Nettet2.3.1 Inter-Alpha-Trypsin Inhibitor Heavy Chains (ITIH2 and 4) Inter-alpha-trypsin inhibitor family proteins are secreted into the blood primarily by the liver (blood concentrations ∼0.15–0.5 mg/mL). Heavy chains represent the main structural unit of the inter-alpha-trypsin inhibitor complex. Nettet18. mar. 2024 · Inter-Alpha-Trypsin Inhibitor Heavy Chain 4 Plays an Important Role in the Development and Reproduction of Nilaparvata lugens 2024 Mar 18;13 (3):303. Authors Jin-Liang Ji 1 , Shan-Jie Han 1 , Rui-Juan Zhang 1 , Jian-Bin Yu 1 , Ya-Bin Li 1 , Xiao-Ping Yu 1 , Guang-Fu Liu 1 , Yi-Peng Xu 1 Affiliation
Nettet22. jan. 2024 · Inter-alpha-trypsin inhibitor heavy chain 4 (ITIH4) regulates immunity and inflammation, but its clinical role in rheumatoid arthritis (RA) patients remains …
Nettet31. jul. 2024 · Abstract Objective: Inter-alpha-trypsin inhibitor heavy chain H3 (ITIH 3) and inter-alpha-trypsin inhibitor heavy chain H4 (ITIH 4) are heavy chains of … the online metalsNettet24. apr. 2024 · In addition to the down-regulation of elastin, we found up-regulation of druggable enzymes and regulators such as the long non-coding RNA H19, inter-alpha-trypsin inhibitor heavy chain family member 5 (ITIH5), lysyl-oxidase (LOX), prolyl 4-hydroxylase subunit alpha 1 (P4HA1), procollagen-lysine 2-oxoglutarate 5-dioxygenase … micro perche boulangerNettet2.3.1 Inter-Alpha-Trypsin Inhibitor Heavy Chains (ITIH2 and 4) Inter-alpha-trypsin inhibitor family proteins are secreted into the blood primarily by the liver (blood … the online mediumNettet9. okt. 1998 · Abstract. To understand more about the human inter-alpha-trypsin inhibitor heavy chain H3 (ITIH3) expression and the relationship between this gene … the online marketing groupNettet8. jul. 2024 · IαI is an approximately 225-kDa complex containing bikunin and two heavy chain (HC) proteins, designated HC1 and HC2 ( Fig. 1 ). 34 IαI is present in many fluid compartments including blood, peritoneal, amniotic, cerebrospinal, and synovial fluids, whereas bikunin is also excreted in the urine. 23, 28, 35 IαI is also present in many … the online policyNettetInter-alpha-trypsin inhibitor heavy chain H2 is a protein that in humans is encoded by the ITIH2 gene. [5] [6] [7] It is known to contain a Gla domain, and thus be dependent for production on post translational modification requiring vitamin K. Its function is also presumably dependent on calcium ions. See also [ edit] Inter-alpha-trypsin inhibitor the online music schoolNettetLUM, lumican; FN1, fibronectin; CLU, clusterin; C1RL, complement C1r subcomponent-like protein; ITIH4, inter-alpha-trypsin inhibitor heavy chain H4; and C9, complement component C9. from ... micro pc wall mount