Web[13]. Indeed, NRF1 binding elements have been identified in genes involved in cellular growth, metabolic energy produc-tion, protein translation and DNA replication/repair [13]. ChIP-on-chip analysis of human T98G glioblastoma-derived cells showed that NRF1 binds to ~691 genes encoding pro-teins regulating cellular growth, DNA replication, DNA re- WebThe set of ChIP-Seq-based NRF1 target genes included known NRF1 targets such as EIF2S1, EIF2S2, CYCS, FMR1, FXR2, E2F6, CD47, and TOMM34. By pathway analysis, the molecules located in the core pathways related to mitochondrial respiratory function were determined to be highly enriched in NRF1 target genes.
NRF1 Antibody - ChIP-seq Grade (C15200013) Diagenode
Web21 aug. 2024 · Moreover, NRF-1 is also present at the core promoter of GABRB1 in human embryonic stem cells (H1-hESC) as detected in ChIP-sequencing (ChIP-seq) datasets of … Web22 jan. 2014 · It is important to note that since we used an antibody that recognizes both Nrf1 isoforms, our ChIP data does not discriminate between the binding of either p65-Nrf1 or p120-Nrf1. In addition, our chip assay data demonstrating Nrf1 differentially binding at the ARE in the presence of hormone correlates with our IP studies that showed … hsn code lead acid battery
(PDF) EglN2 associates with the NRF1-PGC1 complex and controls ...
Web22 okt. 2015 · Our integrative analyses of EglN2 ChIP-Seq and gene expression profiling under hypoxic conditions unveil a unique NRF1 motif enrichment in EglN2-upregulated genes. Mechanistically, by forming an activator complex with PGC1α and NRF1 on chromatin, EglN2 promotes FDXR gene expression and regulates mitochondrial function … Web3 okt. 2024 · Quantification of cDNA or ChIP-DNA samples was conducted via standard quantitative PCR (qPCR) methods using SYBR Green (Thermo Fisher Scientific). The following genes were tested: Acaa2, Gabpa, Mef2a, Nrf1 and Slc25a20 for rat cDNA; Acaa2, Cpt1a, Elovl6, Fads2, Mki67, Scd2, Slc25a20 and Top2a for mouse cDNA and … Web21 mrt. 2024 · NRF1 (Nuclear Respiratory Factor 1) is a Protein Coding gene. Diseases associated with NRF1 include Oncocytoma and Skin Carcinoma In Situ . Among its related pathways are Transcriptional activation of mitochondrial biogenesis and PPARA activates gene expression . hsn code led tv