Phenotype harmonization
WebThe individual predictive performance of each clinical variable, as well as the imaging phenotype based on harmonized (i.e., Phenotype (ComBat)) and non-harmonized (i.e., Phenotype (non-ComBat)) features, were assessed by fitting a Cox proportional hazards regression model and then estimating the C-score associated with the fitted models. Websystem for phenotype harmonization that includes input from phenotype domain and study experts, quality control, documentation, reproducible results, and data-sharing mechanisms. This system was developed for the National Heart, Lung, and Blood Institute’s Trans-Omics for Precision Medicine (TOPMed) program, which is
Phenotype harmonization
Did you know?
WebPhenotype harmonization requires identifying common phenotypes, determining the feasibility of cross-study analysis for each, preparing common definitions, and applying …
WebAug 25, 2024 · Data were harmonized across 5108 participants from a clinical trial of Alzheimer’s disease and three longitudinal cohort studies of cognitive ageing. All analyses were run across all participants and repeated restricting the sample to individuals with unimpaired cognition to identify variants at the earliest stages of disease. WebThe individual predictive performance of each clinical variable, as well as the imaging phenotype based on harmonized (i.e., Phenotype (ComBat)) and non-harmonized (i.e., …
WebFeb 5, 2012 · phenotype harmonization, which can facilitate cross-study comparative analysis and aid researchers in defining the level of phenotype granularity needed to … WebThe Phenotype Harmonization WG will be responsible for defining data format and documentation requirements for Study Site and Affiliate Member-provided phenotype data. These definitions will be chosen to enable generating a Consortium-wide phenotype variable inventory and subsequent harmonization.
WebHarmonization is generally performed by “harmonization unit”, which is defined as a group of subjects whose phenotypes can be similarly processed. In many cases, one study corresponds to one harmonization unit, but more complicated studies may require multiple harmonization units.
WebApr 13, 2024 · At that time I had been working as part of the phenotype harmonization team. I was gaining experience working with phenotype data, including how we were categorizing and harmonizing race and ethnicity. ... helping with content, and editing. My area of focus was the harmonization section since that was what I had experience with at work ... inflate crosswordWebApr 1, 2011 · Phenotype harmonization requires identifying common phenotypes, determining the feasibility of cross-study analysis for each, preparing common definitions, and applying appropriate algorithms. inflate crossword clueWebMar 14, 2024 · Phenotype harmonization requires identifying common phenotypes, determining the feasibility of cross-study analysis for each, preparing common definitions, … inflate bike tire with air compressorWebApr 11, 2024 · Prise en charge transfusionnelle et suivi immunohématologique après allogreffe de cellules souches hématopoïétiques : recommandations de la Société francophone de greffe de moelle et de thérapie cellulaire (SFGM-TC) Transfusion management and immuno-hematological follow-up after allogeneic hematopoietic cell … inflate catheter balloonWebJun 20, 2024 · The harmonized phenotype data and associated documentation have been submitted to National Institutes of Health data repositories for controlled-access by the scientific community. We also provide ... inflated 3d networkWebOct 1, 2024 · The new grant establishes the ADSP Phenotype Harmonization Consortium ( phenotype: the set of observable characteristics of an individual resulting from the … inflate car tire with hand pumpWebAug 24, 2024 · The overarching approach for phenotype harmonization in GLIDE2 is 3-tiered . We begin by considering a broad definition of disease versus health (i.e., 1 or more decayed, missing, filled teeth or surfaces, DMFT/DMFS >0) to allow for the inclusion of the maximum number of participants from all contributing studies. inflate crossword clue 6 letters