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Sumo chains: polymeric signals

Web28 Feb 2010 · Interestingly, a SUMO-binding site in Ubc9 is important for SUMO chain synthesis. Similar to ubiquitin-polymer cleavage by USPs (ubiquitin-specific proteases), … Web10 Jan 2024 · One signaling process initiated by SUMO chains is the SUMO-targeted Ubiquitin ligase (StUbL) pathway. In this evolutionary conserved pathway, poly- (or multi-) …

Decoding the SUMO signal — Discovery - the University of Dundee ...

WebC. M. Guzzo, RNF4-dependent hybrid SUMO-ubiquitin chains are signals for RAP80 and thereby mediate the recruitment of BRCA1 to sites of DNA damage. Sci. ... This is an … Web6 Feb 2024 · Author summary The Small ubiquitin-related modifier (SUMO) is a 100 amino acid protein that is attached to other proteins and thereby regulates nearly all essential … saint francis of assissi clipart https://jackiedennis.com

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WebPrevious studies have shown that, like ubiquitin, SUMO is able to form polymeric chains. These chains are involved in several processes, such as mitosis, meiosis and … Web1 Dec 2009 · Polyubiquitin chains: polymeric protein signals. Curr. Opin. Chem. Biol. 8, 610-616. Potts, P. R. (2009). The Yin and Yang of the MMS21-SMC5/6 SUMO ligase complex in … Web19 Jan 2010 · SUMO chains play roles in replication, in the turnover of SUMO targets by the proteasome and during mitosis and meiosis. Thus signalling via polymers is an exciting … thigh avf

SUMOylation and deSUMOylation at a glance Journal of

Category:Structural insight into SUMO chain recognition and …

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Sumo chains: polymeric signals

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WebPost-translational modification by small ubiquitin-like modifier (SUMO) has emerged as a global mechanism for the control and integration of a wide variety of biological processes … Web27 Jun 2014 · The small ubiquitin-like modifier (SUMO) can form polymeric chains that are important signals in cellular processes such as meiosis, genome maintenance and stress …

Sumo chains: polymeric signals

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WebMonomeric and polymeric forms of SUMO and ubiquitin are covalently ... SUMO-Ub chains may also function as signals that affect lysosomal . ... Hybrid suMo-ub chain receptors. … Web21 Mar 2013 · Ronald T. Hay; Decoding the SUMO signal. Biochem Soc Trans 1 April 2013; 41 (2): 463–473. doi: ... Like ubiquitin, SUMO can form polymeric chains, and these chains …

Web1 Feb 2010 · Search worldwide, life-sciences literature Search. Advanced Search Coronavirus articles and preprints Search examples: "breast cancer" Smith J WebSUMO chains: polymeric signals Alfred C.O. Vertegaal 46–49 Antiviral activity of resveratrol Michela Campagna and Carmen Rivas 50–53 SUMO and ubiquitin modifications during …

Web28 Feb 2010 · Title: SUMO chains: polymeric signals: Author: Vertegaal, A.C.O. Date issued: 2010-02-28: Access: Closed Access: Language: English: Type: Article: Abstract: Ubiquitin … WebOn the contrary, direct detection is possible with mass spectrometry (MS) by the identification of the SUMO–SUMO branched peptide remnant after proteolytic digestion. …

WebThe SUMO monomers display homogeneous fluorescence spots at the single-molecule level, whereas the mixed SUMO chains exhibit nonuniform fluorescence spots with a wide …

WebHence, these signals confirmed the presence of SUMO-2 multimers with a linkage between the C-terminal Gly and Lys 11. Figure 3 SUMO-2 forms polymeric chains via lysine 11 and … thigh avgWeb11 Oct 2010 · The role SUMO plays in meiosis remains largely unknown; however, immunolocalization studies in mammals have detected SUMO at sites of double strand breaks (DSBs) and at centromeric and heterochromatic regions, including the XY body of mouse pachytene spermatocytes [ 9, 10, 11, 12 ]. saint francis prep basketballWeb1 Feb 2010 · SUMO chains: Polymeric signals SUMO chains: Polymeric signals February 2010 Authors: Alfred C O Vertegaal Request full-text Abstract Ubiquitin and ubiquitin-like … saint francis red flash softballWebSmall ubiquitin-like modifiers (SUMOs) regulate virtually all nuclear processes. The fate of the target protein is determined by the architecture of the attached SUMO protein, which … saint francis of paolaWebThe small ubiquitin-like modifier (SUMO) can form polymeric chains that are important signals in cellular processes such as meiosis, genome maintenance and stress response. … thigh artery painWebsignals for proteasome-mediated degradation. Together, these findings suggest multiple, proteasome-independent roles for SUMOs in the cellular response to the accumulation of … thigh avulsionWeb25 Oct 2024 · SUMOylation of proteins plays a key role in modulating neuronal function. For this reason, the balance between protein SUMOylation and deSUMOylation requires fine … thigh atrophy